World champions Germany will visit the San Siro to take on an in-form Italy side in an international friendly on Tuesday.

The Azzurri go into this game with a bit of an injury crisis in defence. The omnipresent duo of Andrea Barzagli and Gergino Chielleni are set to miss the game through injury. This would mean that Alessio Romagnoli will partner Leonard Bonucci in defence.

Antonio Candreva will be touch and go before kick-off against Germany, but is likely to fight off the knock he picked up to start the game. Eder, too, is a major doubt for this game, and might not be risked by coach Giampiero Ventura.

Italy are likely to field a 4-2-2-2 with Ciro Immobile and Andrea Belotti leading the charge for them. Playing in a slightly withdrawn role will be the dynamic duo of Giacomo Bonaventura and Antonio Candreva. Matteo Darmian and Mattia de Sciglio are likely to start as full-backs.

TURIN, ITALY - JANUARY 26: Mattia De Sciglio of AC Milan in action during the TIM Cup match between US Alessandria and AC Milan at Olimpico Stadium on January 26, 2016 in Turin, Italy. (Photo by Valerio Pennicino/Getty Images)

TURIN, ITALY – JANUARY 26: Mattia De Sciglio of AC Milan in action during the TIM Cup match between US Alessandria and AC Milan at Olimpico Stadium on January 26, 2016 in Turin, Italy. (Photo Courtesy: Valerio Pennicino/Getty Images)

For Germany, the injuries are significant and may play a key role in shaping the outcome of this contest. In goal, Manuel Neuer is set to miss out with Joachim Low confirming that Bernd Leno will start between the sticks for the game against Italy, ahead of Marc Andre ter-Stegen who played the entire game against San Marino.

Meanwhile, midfield maestro Toni Kroos has withdrawn from the squad due to a broken metatarsal and is ruled out for the entire calendar year. Bayer Leverkusen prodigy Julian Brandt has also left the national side because of an injury.

This would see Julian Weigl slot into the side and will partner former Borrusia Dortmund teammate Ilkay Gundogan at the heart of midfield. Serge Gnabry goes into the game against Italy on the back of a hat-trick on his international debut, and looks set to start on the left wing.

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