Pierre-Emerick Aubameyang is fit to start while Lucas Torreira partner Granit Xhaka in midfield as Arsenal get set to take on Crystal Palace at Selhurst Park.
Arsenal will be looking to return to winning ways when they take on a resurgent Everton side at Goodison Park on Saturday.
Unai Emery confirmed that Nicolas Pepe is available to be picked on Saturday despite arriving late from international duty as Arsenal face Southampton.
Unai Emery has chosen to field what potentially looks like a 3-5-2 formation, with Alexandre Lacazette and Pierre-Emerick Aubameyang leading the Arsenal attack.
Aaron Ramsey is on the bench again for Arsenal, with Alex Iwobi retaining his place in the starting eleven as the Gunners take on Crystal Palace
Arsenal mounted a late comeback to snatch a 4-3 win over Leicester City to kick off their Premier League campaign on a positive note.
Arsenal will continue their push for a UEFA Champions League spot as they travel to face Southampton
Confirmed lineups for Arsenal's fixture against Crystal Palace
Arsenal cruised to a 3-0 victory over West Ham in the English Premier League on Wednesday night
Italy host Albania tomorrow night at the Stadio Renzo Barbera for their Group G 2018 FIFA World Cup Qualifier