Ousmane Dembele is in line to make his first start of the season but Gavi could be rested when Barcelona take on Real Betis in La Liga on Saturday.
Barcelona manager Xavi Hernandez has responded to the club's links to Manchester City forward Ferran Torres ahead of the January transfer window.
Julian Alvarez's rising stock has attracted interest from some of Europe's giants, with Newcastle United becoming the latest club keen on the Argentine forward.
Frenkie de Jong, Memphis Depay and Philippe Coutinho were on target as Barcelona defeated Villarreal 3-1 at El Madrigal in La Liga on Saturday night.
Ousmane Dembele is in contention to start while Sergino Dest and Abde Ezzalzouli should feature from kickoff when Barcelona take on Villarreal in La Liga.
Barcelona squandered a serious opportunity to qualify for the UEFA Champions League knockout phases, leaving their fate hanging in the balance.
Barcelona manager Xavi could make minor tweaks to the side facing Benfica with Gavi back in midfield and Ronald Araujo replacing Eric Garcia.
Xavi Hernandez will be aiming to continue his winning start as Barcelona manager when they host Benfica in the Champions League.
A new era begins at Barcelona this weekend as they gear up for their first game under new manager Xavi Hernandez when they host local rivals Espanyol.
Barcelona President Joan Laporta has not ruled out a sensational return for former superstars Lionel Messi and Andres Iniesta