Wilfried Zaha's penalty was enough to secure three points for Crystal Palace as Watford suffer relegation to the Championship.
Crystal Palace will look to move up into the top half of the Premier League table as they face relegation favourite Watford at Selhurst Park.
Wilfried Zaha steals the winner for Crystal Palace to help the team achieve their first comeback victory this season at St Mary's.
Two sides in terrible form will face off in search of all-important win, as safety remains the priority for Southampton and Crystal Palace.
Leeds United picked a key point away at Selhurst Park as Crystal Palace failed to break down the visitors on Monday night.
Reece James and Ruben Loftus-Cheek impressed as Chelsea secured a 2-0 victory over Crystal Palace to progress to the finals of the 2021/22 FA Cup.
Mid-table battlers Leicester City and Crystal Palace will lock horns at the King Power Stadium, with both teams having little to play for in the Premier League.
Wilfried Zaha ran rings around the Arsenal defence as Crystal Palace registered a shocking 3-0 victory over the Gunners on Monday.
Paul Merson has urged Arsenal to consider signing Wilfried Zaha to replace Nicolas Pepe, insisting the Crystal Palace ace could make a huge difference.
Crystal Palace booked their place in the FA Cup semi-finals as they romped to a 4-0 home victory over Everton on Sunday afternoon.