Nicolas Pepe was the super sub as he scored two late free-kicks to save Arsenal's blushes and complete a 3-2 comeback win over Vitoria SC on Thursday.
Alexandre Lacazette and Kieran Tierney return while Hector Bellerin is the Arsenal skipper for their Europa League tie against Vitoria de Guimaraes.
Hector Bellerin and Rob Holding are among eight players set to return to the starting lineup when Arsenal welcome Vitoria de Guimaraes to the Emirates on Thursday.