Barcelona cruised to an easy 2-0 victory over Sporting Lisbon at Camp Nou, with the goals coming from Paco Alcacer and Sporting's Jeremy Mathieu.
Coutinho has been entrusted with the captain's armband for Wednesday's tie at home against Spartak Moscow in the Champions League.
The Blues secured qualification to the Round of 16 with a tense, hard fought and largely frustrating draw at Stamford Bridge against Diego Simeone's Atletico Madrid
Zinedine Zidane is likely to make minimal changes and put out a strong Real Madrid starting eleven for the Champions League tie against Borussia Dortmund.
Chelsea secured second place in Group C and confirmed qualification to the knockout stages of the Champions League with a tense 1-1 draw against Atletico Madrid at Stamford Bridge.
In their final match of Group H, group winners Tottenham Hotspur host Cypriot side APOEL Nicosia at Wembley.
Real Madrid host Borussia Dortmund in the last game of their respective group stage fixtures in Group D of the UEFA Champions League
Samuel Umtiti is set for a long spell on the sidelines but Valverde has recalled a couple of players as Barcelona take on Sporting in UEFA Champions League.
Chelsea stomped FK Qarabag by 4 goals to Nil in Baku on Wednesday to secure three more points in the UEFA Champions League.
Real Madrid strolled to a comfortable 6-0 win in Cyprus against APOEL Nicosia to clinch qualification into the knockout phase of the UEFA Champions League.