Tottenham travel to Rochdale for their 5th Round FA Cup clash as Spurs' look to advancing to the quarter-finals of the competiton
Real Madrid host Villarreal at the Santiago Bernabeu on Saturday, hoping to continue to try and close the gap between themselves and third-placed Valencia.
Barcelona will look to hold on to their lead at the top of table, when they visit Estadio de la Ceramica to take on Villarreal on Sunday night.
Sevilla will battle it out for fourth position against a Real Madrid side plagued by suspensions and injuries, at the Santiago Bernabeu on Saturday.
Real Madrid will be without some major players, while Tottenham will be boosted by the return of key personnel as the two sides prepare to face off at Wembley.
Chelsea boss Antonio Conte confirmed the absence of two key players from the trip to Bournemouth, while also dismissing rumours of his own future at the club
Antonio Conte has a number of selection headaches ahead of him as Chelsea host Marco Silva's fourth placed Watford today at Stamford Bridge
After a disappointing draw at Watford on opening day, Liverpool come home to Anfield to entertain Crystal Palace - a side they don't particularly share the greatest recent record against.
Chelsea face Arsenal at Wembley in the final of the FA Cup, as they look to cap their season off with a domestic double.
Daniel Sturridge and Roberto Firmino are set to start at the expense of Divock Origi as Liverpool fight to secure Champions League football against Middlesbrough.
