Manchester City will be hoping to keep pace with Liverpool when they welcome Southampton to the Etihad Stadium on Saturday.
Manchester City will lock horns with a struggling Southampton side in the Carabao Cup Round of 16 stages at the Etihad Stadium on Tuesday night.
Chelsea enter the international break with top four in sight, as they beat Southampton 4-1 at St. Mary's Stadium on Sunday afternoon.
Tammy Abraham and Mason Mount continued their splendid start to the season, as Chelsea cruised to a 4-1 win over Southampton on Sunday.
Callum Hudson-Odoi makes his first Premier League start of the season as Chelsea get set to take on Southampton at St. Mary's Stadium.
N'Golo Kante could be rested by Frank Lampard when Chelsea take on Southampton at St. Mary's Stadium on Sunday afternoon.
Chelsea will aim to go into the international break by securing a top four spot when they travel to St. Mary's Stadium to take on Southampton on Sunday.
Mauricio Pochettino and his Tottenham side will be looking to end a miserable run of games to begin a new chapter against a travelling Southampton side
Daniel James was one of the few positives as Manchester United played out a disappointing 1-1 draw with Southampton at St. Mary's on Saturday
Manchester United are now three games without a win as a ten-man Southampton held Ole Gunnar Solskjaer & co. to a frustrating 1-1 draw at St. Mary's on Saturday.