Julen Lopetegui will be privy to his first Madrid derby in La Liga as Real Madrid look to bounce back with a win over Atletico Madrid on Saturday.
Atletico Madrid's Spanish midfielder Saul Niguez is reportedly courting interest from Premier League giants Arsenal.
Barcelona are reportedly looking to bring Saul in from Atletico Madrid in the summer, with Lionel Messi preferring the midfielder over Antoine Griezmann.
Messi, Suarez, Neymar all start for Barcelona as they host Simeone's Atletico Madrid led by Antoine Griezmann in the attack.
Tottenham Hotspur surprised everyone with their superlative performances in the 2015-16 season, with an end of season crash seeing them lose out to Leicester City and Arsenal and settle for third place. This summer transfer window presents the perfect opportunity for Mauricio Pochettino to build a team capable of vying for domestic and European honours next season.
Portuguese manager Jose Mourinho is set to oversee a squad overhaul at Manchester United and his first priority will reportedly be to sign one of his best former players from Premier League rivals Chelsea.