Raphael Varane and the rest of the Manchester United defenders were abysmal as Brighton & Hove Albion handed them a 4-0 defeat on Saturday.
Cristiano Ronaldo starred again while Raphael Varane and Juan Mata also impressed as Manchester United beat Brentford 3-0 in the Premier League.
Raphael Varane replaces Harry Maguire in defence, while Cristiano Ronaldo, Scott McTominay and Jadon Sancho start for Manchester United against Arsenal.
Marcus Rashford is likely to replace Cristiano Ronaldo, while Fred and Raphael Varane remain unavailable for Manchester United against Liverpool.
Scott McTominay is set to return but Cristiano Ronaldo and Raphael Varane could miss out when Manchester United face Manchester City on Sunday.
Former Tottenham and Aston Villa manager Tim Sherwood has blasted Manchester United defender Raphael Varane, claiming he has been 'terrible'.
Raphael Varane is set to return to the lineup while Marcus Rashford should also feature from kickoff when Manchester United face Leeds United.
Bruno Fernandes and Raphael Varane will return when Manchester United and Wolverhampton Wanderers face off on Monday.
Raphael Varane and Edinson Cavani have recovered from their injuries but Paul Pogba is unavailable as Manchester United prepare to face Newcastle United.
Inter Milan are linked with a surprise move for Raphael Varane, who only joined Manchester United in the summer