Manchester City are currently seven points ahead of Arsenal as they enter the tie as favourites yet the Gunners might cause an upset.
Real Madrid will be looking to defend their 2-1 lead when they play host to Bayern Munich in the Champions League quarter-final.
Juventus will play host to FC Barcelona in the first leg of their UEFA Champions League quarter-final tie.
After seeing off Napoli in the Champions League, Real Madrid will shift their attention to Real Betis, as they look to regain their place at the summit of the La Liga.
After having dropped points against Valencia and UD Las Palmas, Real Madrid travel to Gipuzkoa to face SD Eibar in what will be their most important League fixture of the season.
After having their lead at the top of the La Liga shortened by Valencia, Real Madrid will look to get back to winning ways when they travel to the El Madrigal to face Villarreal CF
Antonio Conte will hope to get his side back to winning ways as they travel to the West Midlands today to face Wolverhampton Wanderers in the Fifth Round of the FA Cup.
Real Madrid host Napoli in the first leg of the UEFA Champions League Round of 16 match on Wednesday.
Burnley are set to host league leaders Chelsea at Turf Moor as they look to become the first side to inflict defeat the on Blues since Tottenham in January.
If they are to keep themselves alive in the title race, Barcelona will have to get past an Athletic Bilbao side seeking revenge for their exit from the Copa Del Rey last month.