Arsenal await another away test as they travel to Watford in pursuit of a top-four place and their first Premier League clean sheet away from home this season.
Pep Guardiola will look for an immediate response from his team against Crystal Palace, who will be hoping to do the double over Manchester City.
The most anticipated Premier League clash of the weekend comes our way on Sunday from Anfield, when leaders Liverpool host top four hopefuls Chelsea.
Manchester United will be desperate to get back to winning ways when they welcome West Ham United to Old Trafford on Saturday evening.
We take a look at some of the potentially profitable markets from the 34th gameweek of the Premier League featuring Liverpool vs Chelsea and more.
Arsenal are reportedly interested in former Aston Villa star Jordan Veretout and scouring the prospect of a summer move for the Fiorentina playmaker.
Jurgen Klopp has chosen to just shuffle his midfield in what is a relatively unchanged Liverpool eleven from their win over Tottenham as they face Southampton.
Virgil Van Dijk is fit enough to feature against his former club Southampton as Liverpool aim to return to the top of the Premier League.
Liverpool will hope to regain their spot atop the Premier League table when they travel to St. Mary's on Friday to face relegation-threatened Southampton.
Arsenal are reportedly considering a summer swoop to land Bournemouth star Ryan Fraser in the summer transfer window to add width to their attack.