Chelsea play hosts to Hull City in gameweek 22 of the Premier League on Sunday as they look to maintain their stronghold at the top of the English top flight.
An in-form Chelsea will host Eddie Howe's Bournemouth on boxing day, as they look to continue their historic winning streak at the expense of the Cherries.
Chelsea travel to Selhurst Park to face a Crystal Palace side ravaged by injury, as the Blues look to match equal their best ever Premier League match-winning streak.
Antonio Conte and his men will play host to Tony Pulis' West Bromwich Albion as Chelsea look to win their ninth consecutive Premier League game and extend their lead on the top
Arsenal travel to Switzerland for their final UEFA Champions League Group Stage fixture against FC Basel.
Antonio Conte's Chelsea face their biggest test this season in the former of Pep Guardiola's Manchester City, who are looking to leapfrog the Blues into first place with a victory.
Arsenal host Bournemouth at The Emirates on Sunday afternoon, with Jack Wilshere set to watch on from the sidelines
Chile and Colombia face each other in what is one of the most important fixtures in the CONMEBOL world cup qualifiers on Thursday evening.
Jorge Sampaoli's high flying Sevilla will welcome a wounded Barcelona side who will look to try and get back to winning ways against a side that is yet to be defeated at home this season.
Arsenal host a Championship bound Aston Villa side at the Emirates, as the Gunners look to end a disappointing season on a positive note.