The suspended Jordi Alba will be one of five first-team players unavailable when Barcelona pay a visit to San Mames to face Athletic Bilbao on Sunday.
Barcelona were made to work hard for all three points by a spirited Leganes side, with Ousmane Dembele inspiring a 3-1 win at Camp Nou on Sunday.
Barcelona completed the turnaround in their Round of 16 tie against Levante in stunning fashion, coasting to a 3-0 win at Camp Nou on Thursday.
Defending champions Barcelona will finish 2018 as the La Liga leaders after they eased past Celta Vigo in a 2-0 win at Camp Nou on Saturday evening.
A late strike from Lucas Moura deprived Barcelona from a victory in their final UEFA Champions League group game against Tottenham Hotspur on Tuesday
Ousmane Dembele came off the bench to snatch a point for Barcelona as the La Liga leaders drew 1-1 with rivals Atletico Madrid at the Wanda Metropolitano on Saturday
France and Uruguay are set to lock horns in what will be a replay of the 2018 FIFA World Cup quarter-final clash at Stade de France on Tuesday.
Liverpool are reportedly plotting a shock £85 million move to land Ousmane Dembele from Barcelona in the January transfer window
Barcelona are reportedly willing to throw in Ousmane Dembele as a makeweight to sign Danish playmaker Christian Eriksen from Tottenham Hotspur.
Ousmane Dembele's future at Barcelona. The Hard Tackle takes a look at three possible destinations for the out-of-favour French winger