Marcus Rashford is fit to feature while Eric Bailly and Bruno Fernandes should return to the lineup when Manchester United face Sheffield United.
Victor Lindelof should return to the lineup while Marcus Rashford and Scott McTominay will also start when Manchester United face Liverpool in the FA Cup.
Donny van de Beek is in line to start while Mason Greenwood and Juan Mata should feature from the kick-off when Manchester United face Watford in the FA Cup.
Dean Henderson is expected to replace David de Gea in goal when Manchester United take on Manchester City in the semi-finals of the Carabao Cup.
Scott McTominay is an injury doubt while Marcus Rashford and Anthony Martial are expected to start when Manchester United take on Leicester City on Saturday.
Ole Gunnar Solskjaer is expected to ring in the changes when Manchester United face in-form Everton in the Carabao Cup quarterfinal on Wednesday.
With the summer transfer window now slammed shut, The Hard Tackle takes a closer look at Manchester United's performance in the market.
Marcus Rashford and Bruno Fernandes are set to return to the starting XI while Alex Telles remains unavailable as Manchester United face Arsenal on Sunday.
Ole Gunnar Solskjaer may have to make some tough decisions in terms of his team selection as Manchester United face Newcastle United on Saturday.
Eric Bailly makes his first Premier League start of the season while Donny van de Beek is benched as Manchester United face off against Tottenham.