Manchester United will be desperate to return to winning ways and take a grip on the top four race when they take on Everton at Goodison Park.
Manchester United were booted out of the UEFA Champions League as Barcelona handed them a 3-0 defeat at Camp Nou on Tuesday.
Marcus Rashford starts in place of Romelu Lukaku, with Ole Gunnar Solskjaer making three other changes for Manchester United's game against Barcelona.
Alexis Sanchez is in contention to feature when Manchester United take on Barcelona in the UEFA Champions League quarter-final second leg at Camp Nou.
A spot in the Last Four stage of the UEFA Champions League will be decided when Barcelona host Manchester United at Camp Nou in the quarter-final second leg.
Manchester United needed two penalties from Paul Pogba to garner all three points as they beat West Ham United 2-1 at Old Trafford on Saturday.
Anthony Martial is among five changes made by Ole Gunnar Solskjaer to his most recent side as Manchester United prepare to host West Ham United at Old Trafford.
Anthony Martial will return while Luke Shaw is suspended as Manchester United prepare to welcome West Ham United to Old Trafford on Saturday.
Manchester United will be desperate to get back to winning ways when they welcome West Ham United to Old Trafford on Saturday evening.
Manchester United star Paul Pogba's relationship with manager Ole Gunnar Solskjaer has reportedly hit rocky terrain, with the player now seeking a transfer.