Brighton's comeback victory condemned West Ham United to a seventh-placed finish, only good enough to qualify for the UEFA Europa Conference League.
West Ham United could only manage a draw at home to Burnley in a game that was marred by Ashley Westwood's gruesome injury.
Tottenham host West Ham United in a key clash in the top-four race, as both teams seek three points to improve their chances.
Declan Rice and Tomas Soucek produced a midfield masterclass as West Ham beat Sevilla 2-1 on aggregate to reach the UEFA Europa League quarter-finals.
West Ham have a tough assignment ahead as they take on Europa League experts Sevilla in a Round of 16 tie on Thursday.
A hapless West Ham United succumbed to a heavy defeat against Southampton and crashed out of the FA Cup disappointingly
West Ham United and Newcastle United will be desperate to grab all three points when they face off at the London Stadium on Saturday.
West Ham United are reportedly interested in a move for Breel Embolo, as David Moyes seeks a striker to complement and compete with Michail Antonio.
Premier League strugglers Watford host a West Ham United side aiming to stay alive in the race for Champions League places.
West Ham United gave their fans little festive joy as an abject home loss to Southampton saw them lose ground in the race for a top-four finish.