Tottenham will clash against German league leaders Borussia Dortmund for the first leg of their UEFA Champions League Round of 16 tie on Wednesday night.
Tottenham Hotspur will be looking to keep the pressure on Liverpool and Manchester City when they welcome Leicester City to Wembley on Sunday.
With Maurizio Sarri under pressure, Chelsea could reportedly look at Tottenham manager Mauricio Pochettino as a potential candidate to replace the Italian.
Tottenham hope to go above Manchester City as they face Newcastle United who look to make two big scalps in one week after beating the champions in midweek.
Tottenham host Watford in the Premier League with Mauricio Pochettino's men looking to put the cup disappointments behind them and get back into their rhythm.
A place in the Carabao Cup final will be on the line when Chelsea welcome Tottenham Hotspur to Stamford Bridge in the semi-final second leg.
Manchester United have reportedly added Gareth Southgate to their managerial shortlist, as fears grow over Mauricio Pochettino's availability.
It's back to back cup games for Chelsea and Tottenham, as they meet in the first leg of their Carabao Cup semi-final at Wembley on Tuesday night.
Tottenham Hotspur will be raring to bounce back after their weekend defeat, when they travel to Wales to face off against Cardiff City on Tuesday.
Tottenham Hotspur will be aiming to continue their charge up the Premier League table when they welcome Wolverhampton Wanderers to Wembley on Saturday.