The Premier League Champions get their title defence underway by hosting Sean Dyche's Burnley at Stamford Bridge on Saturday
Real Madrid travel to Galicia to face Eduardo Berizzo's Celta de Vigo, in what will be the fourth meeting between the two sides this season
Chelsea play hosts to Steve Agnew's Middlesbrough on Monday, as they look to capitalise on Spur's defeat to move seven points clear at the summit of the League.
Zinedine Zidane and his men will be hosted by Granada CF at Los Cármenes, as they look to keep the pressure on arch rivals Barcelona at the summit of the La Liga.
Real Madrid will be hosted by a Napoli side desperate to cause an upset at the Stadio San Paolo, in the second leg of their UEFA Champions League Round Of 16 tie.
After having dropped points against Valencia and UD Las Palmas, Real Madrid travel to Gipuzkoa to face SD Eibar in what will be their most important League fixture of the season.
After having their lead at the top of the La Liga shortened by Valencia, Real Madrid will look to get back to winning ways when they travel to the El Madrigal to face Villarreal CF
Burnley are set to host league leaders Chelsea at Turf Moor as they look to become the first side to inflict defeat the on Blues since Tottenham in January.
Chelsea welcome League One side Peterborough United to Stamford Bridge for their third round FA Cup tie.
An in-form Chelsea will host Eddie Howe's Bournemouth on boxing day, as they look to continue their historic winning streak at the expense of the Cherries.