Timo Werner and Mateo Kovacic are set to miss out with injuries but Cesar Azpilicueta should start when Chelsea face Leicester City in the Premier League.
Cristiano Ronaldo was once again Manchester United's saviour as they managed to hold Chelsea to a 1-1 draw at Old Trafford on Thursday.
Thomas Tuchel could change the team's shape, with key stars Jorginho, Kai Havertz and Trevoh Chalobah expected to return against West Ham United.
Jamie O'Hara blasted Kai Havertz's shocking dive, insisting the German should have been sent off rather than being shown just the yellow against Crystal Palace.
Mason Mount and Timo Werner stood out as Chelsea ran riot against Southampton with a 6-0 win at St. Mary's on Saturday.
Karim Benzema stole the show with a hat-trick while Andreas Christensen endured a torrid game as Real Madrid beat Chelsea 3-1 in the UEFA Champions League.
Chelsea will hope to reach the UEFA Champions League quarter-finals when they take on Lille in the Round of 16 second leg on Wednesday.
A late strike from Kai Havertz helped Chelsea secure a hard-fought 1-0 victory over a steely Newcastle United in the Premier League on Sunday.
Mateo Kovacic, Mason Mount and Kai Havertz stood out as Chelsea earned a hard-fought 3-1 win over Norwich City at Carrow Road on Thursday.
Reece James stood out on his return to the starting lineup as Chelsea beat Burnley 4-0 at Turf Moor to consolidate their position on the Premier League table.