Adam Lallana and Philippe Coutinho are expected to be in the matchday squad as Liverpool host Southampton.
Liverpool will be without the services of their captain Jordan Henderson for the game against Watford
Jordan Henderson and Adam Lallana are set to miss Liverpool's away fixture against West Brom on Sunday.
Liverpool will be without the services of two midfielders in Adam Lallana and Jordan Henderson for the Merseyside derby against Everton on Saturday.
Jordan Henderson is expected to miss Liverpool's trip to Manchester City on Sunday
As confirmed by Jurgen Klopp in the pre-match conference, Jordan Henderson and Daniel Sturridge miss out on the match, with Emre Can slotting in for the cultured midfielder.
Liverpool will be without the English duo of Jordan Henderson and Daniel Sturridge as they host Arsenal at Anfield on Saturday.
Jurgen Klopp has chosen to start Joel Matip after the Cameroonian was cleared to play for Liverpool in the crucial EFL Cup tie while Jordan Henderson also gets the nod despite struggling with his fitness before the game.
Liverpool Confirmed Lineup vs Sunderland: Sturridge in for Henderson; Borini faces former club
Both England and Spain are coming off the back of dominating victories against Scotland and Macedonia respectively in World Cup qualifying matches, so it is likely that both sides wouldn't go into this tie with the same vigour, given that it is only a friendly.