Shkodran Mustafi and Alexandre Lacazette have been recalled by Arsene Wenger as Arsenal host Tottenham at the Emirates in the North London Derby.
Real Madrid have reportedly made Harry Kane their priority to bolster their attack, with Karim Benzema struggling for form
Real Madrid will be without some major players, while Tottenham will be boosted by the return of key personnel as the two sides prepare to face off at Wembley.
Eric Bailly could return to Jose Mourinho's matchday squad when Manchester United host Tottenham at Old Trafford on Saturday
Liverpool's struggles in the Premier League continued on Sunday as Tottenham enjoyed an emphatic 4-1 win over the Reds.
Real Madrid are reportedly considering a sensational €200 million deal to land Harry Kane from Tottenham next summer.
Tottenham continued their fine run of away form on Saturday as they handed a 4-0 thumping to Huddersfield Town at the John Smith's Stadium.
Tottenham Hotspur will hope to continue their unbeaten away run as they travel to face newly-promoted Huddersfield Town on Saturday.
Tottenham Hotspur and Swansea City face off under the Wembley arch in Saturday's late kick off in the Premier League.
Harry Kane netted a stunning brace to propel Tottenham Hotspur towards breaking the dreaded Wembley curse, as they beat Borussia Dortmund 3-1