Liverpool will be hoping to return to the top of the Premier League table when they host Tottenham Hotspur at Anfield in a crucial encounter for both sides.
Southampton hosts Tottenham with both sides hoping to bounce back from their difficult spell in recent games.
Real Madrid have been told to cough up a staggering £310 million if they are to secure the services of Harry Kane from Tottenham Hotspur.
After progressing from the Champions League group stages, Tottenham will be in high spirits when they host Burnley at Wembley and look for all three points
Reigning Spanish champions Barcelona are reportedly plotting a summer swoop for Tottenham Hotspur and England superstar Harry Kane.
Arsenal prepare to host Tottenham for the 196th North London Derby at the Emirates Stadium as both teams aim to close the gap to the top of the table
Tottenham hosts Inter Milan looking for a victory in this clash to keep their hopes of qualification into the next round alive, as a defeat or draw could send the Italians through
Tottenham makes a short trip to their London rivals Crystal Palace as Mauricio Pochettino's in-form side look to keep pace with other top sides
Tottenham will be hoping to keep their UEFA Champions League campaign alive when they welcome PSV Eindhoven to Wembley on Tuesday
PSV and Tottenham face each other in a crunch Champions League tie, where the losers will likely lose any hopes of qualifying for the knockout phase.