Italy will be aiming to book their ticket to the FIFA World Cup 2022 qualifiers playoff final when they take on North Macedonia on Thursday.
A late show by Memphis Depay and Steven Bergwijn helped the Netherlands secure a spot in the 2022 FIFA World Cup at the expense of Norway.
France, who have already qualified for the World Cup in Qatar, face Finland, who will be aiming to secure a second-place finish in Group D.
Wales will host Belgium in Cardiff on Tuesday evening, knowing that even a draw would be enough to seal second place in Group E.
Alvaro Morata made the difference as Spain eked out a 1-0 win over Sweden on Sunday to book their place at the 2022 FIFA World Cup.
Italy will hope to book their place at the 2022 FIFA World Cup when they take on Northern Ireland at Windsor Park on Monday.
Memphis Depay produced a valiant effort, but it essentially came to nought as the Netherlands were held to a 2-2 draw by Montenegro on Saturday.
Portugal will aim to avoid defeat as they look to finish as group winners when they host Serbia in a top of the table clash this weekend.
An automatic berth at the 2022 FIFA World Cup will be up for grabs when Spain welcome Sweden to Estadio de La Cartuja on Sunday.
France will look to get a step closer to the 2022 FIFA World Cup when they take on European minnows, Kazakhstan on Saturday.