Fabio Carvalho will make his first start for Liverpool, while Darwin Nunez is available for the Merseyside derby against Everton on Saturday.
Liverpool will hope to continue rising through the Premier League standings when they take on Everton at Goodison Park on Saturday.
Roberto Firmino will replace the suspended Darwin Nunez when Liverpool and Manchester United face off at Old Trafford on Monday night.
A Luis Diaz stunner rescued a point for ten-man Liverpool against Crystal Palace, with Wilfried Zaha shining for the visitors.
Darwin Nunez makes his first Liverpool start and Nat Phillips replaces Joel Matip while Harvey Elliott comes into midfield.
Jurgen Klopp will be forced to make big changes, with Joe Gomez and Harvey Elliott set to start in place of Joel Matip and Thiago Alcantara.
Liverpool will be looking for their first win of the season after a stuttering start as they welcome a hungry Crystal Palace side to Anfield
The defensive unit faltered, but Darwin Nunez was impressive on debut as Liverpool held Fulham to a 2-2 draw in their opening Premier League fixture.
Darwin Nunez will make his competitive debut for Liverpool, while Alisson Becker will be fit to start when the Reds take on Fulham at Craven Cottage on Saturday.
Liverpool kicked off the 2022/23 campaign on a winning note as they defeated Manchester City 3-1 to lift the FA Community Shield.