Manchester City manager Pep Guardiola has no fresh injury concerns to deal with as the Citizens host Burnley in their first match of 2017.
Burnley opened their Premier League account in some style as a pair of lethal strikes from their forwards Sam Vokes and Andre Gray gave the club their first win.
Klopp has dropped the much criticized Alberto Moreno for Liverpool's game against Burnley, while injury prone Daniel Sturridge returns to the starting XI for the Reds.
After winning a seven-goal thriller against Arsenal in their Premier League opener, the Reds travel to Turf Moor hoping to make it two wins out of two.
Liverpool travel to Turf Moor aiming for their second win in a row, while Burnley would want to bounce back from their opening day disappointment.
After being our of action for more than two months, Alexis Sanchez took over where he left off as he played a match winning performance in Arsenal's FA Cup tie against Championship side Burnley.
The fourth round clash of the FA cup between the third spot holders of both the Premier League and Championship at Emirates might end in favour of the home team as they look to extend their cup run and make history by landing the trophy for a consecutive third season.
Arsenal travelled to Turf Moor to face Burnley and managed to eke out a 1-0 win that saw their winning run stretch to eight games, a sequence of wins that no other team has managed this season so far.
Burnley play hosts to Arsenal in Round 32 of the Premier League, and both teams will be looking to score maximum points in this game.
TheHardTackle takes a closer look at 4 games that are critical in this season's relegation battle, which is becoming as tight as the battle for a place in the Top 4.