Brandon Williams starts at right-back while Scott McTominay and Odion Ighalo feature for Manchester United in their Europa League Round of 16 tie against LASK.
A second half goal from Juan Mata fired Manchester United to a narrow 1-0 win over Wolves in their FA Cup third round replay at Old Trafford.
Academy product Brandon Williams is set to feature from the kick-off when Manchester United take on Chelsea in the Carabao Cup on Wednesday.
An Anthony Martial penalty in the first half was enough for Manchester United to defeat Serbian giants Partizan Belgrade 1-0 in the UEFA Europa League.
An atrocious midfield and attacking display paved the way for another frustrating night on the road as Manchester United played out a tame 0-0 draw with AZ Alkmaar.
Brandon Williams makes his full debut for Manchester United, who will be skippered by David de Gea, as they get set to take on AZ Alkmaar in the UEFA Europa League.
Can the injury to Luke Shaw be the starting point of another success story for the Manchester United academy, with Brandon Williams tipped to be called up?