Jose Mourinho is expected to reinstate both Marcus Rashford and Anthony Martial into the starting lineup as Manchester United take on Bournemouth.
Manchester United will be looking to bounce back from their defeat to rock-bottom West Brom as they travel to face Bournemouth on Wednesday.
Sadio Mane, Mohamed Salah and Roberto Firmino all got into the act as Liverpool beat Bournemouth 3-0 at home.
Liverpool manager Jurgen Klopp will have club captain Jordan Henderson available for selection, when his side take on Bournemouth.
Liverpool will welcome Eddie Howe's AFC Bournemouth to the Anfield on Saturday, as the attention shifts back to the Premier League
The reigning champions were put to the sword by Eddie Howe's fearless Bournemouth side, after a second half masterclass at Stamford Bridge.
Ross Barkley has been handed a rare start in a Chelsea shirt as Thibaut Courtois returns for the match against AFC Bournemouth.
On the final day of January, Chelsea welcome Eddie Howe's Bournemouth to Stamford Bridge a Gameweek 25 encounter of the Premier League.
Reigning champions Chelsea host AFC Bournemouth at Stamford Bridge tonight in matchday 25 of the Premier League.
Arsenal travel to Bournemouth on the back of a winless start to 2018 and hopes a win would boost their confidence in the top-four race.