Isco starts for Real Madrid with Gareth Bale fit enough to only make the bench as Los Blancos go up against Juventus in the final of the UEFA Champions League.
Gareth Bale has returned to the first team squad after an injury layoff that saw him miss out on a number of key games.
Real Madrid were handed a significant blow in the title race as Barcelona beat Los Blancos 3-2 in the El Clasico on Sunday night
Real Madrid fans would be elated to see Gareth Bale in the starting eleven against Barcelona in El Clasico after the Welsh was doubtful ahead of the tie.
Neymar is suspended for Barcelona while Gareth Bale could be set to be on the sidelines for Real Madrid as the Bernabeu plays hosts to the El Clasico on Sunday.
Real Madrid are set to take to the field without Gareth Bale as they aim to overcome Bayern Munich en route to the UEFA Champions League Semi-Finals.
Sporting Gijon host Real Madrid on Saturday night in the Spanish La Liga
Zinedine Zidane is likely to reinstate Gareth Bale and Cristiano Ronaldo in the starting lineup as they host Atletico Madrid on Saturday.
Zinedine Zidane has chosen to exclude Gareth Bale and Cristiano Ronaldo from the traveling squad as he takes his Real Madrid side to face CD Leganes.
Chris Coleman takes his Welsh side to face Ireland in an important Group D encounter of FIFA World Cup Qualifiers, with both teams yet to taste defeat.