One of the four semi-finalists of the UEFA Europa League will be confirmed when Valencia host Villarreal at Mestalla in the quarter-final second leg on Thursday.
Arsenal holds a two-goal advantage over Napoli, although their away form in the Europa League might come back to bite them at the San Paolo
Two Eagles will lock horn against each other as Eintracht Frankfurt host SL Benfica in the 2nd leg of their quarterfinal encounter in the UEFA Europa League
Juventus crashed out of the UEFA Champions League as they were beaten 2-1 by Dutch giants AFC Ajax in the quarter-final second leg at home on Tuesday night.
Manchester United were booted out of the UEFA Champions League as Barcelona handed them a 3-0 defeat at Camp Nou on Tuesday.
Chelsea will be looking to defend their narrow 1-0 lead from the first leg when they host Slavia Prague in the UEFA Europa League on Thursday.
Barcelona secured safe passage through to the UEFA Champions League semi-finals after completing a 4-0 aggregate win over Manchester United on Tuesday.
Real Madrid had to come back from a goal down to salvage a point thanks to Karim Benzema as they held Leganes to a 1-1 draw at Butarque on Monday.
Liverpool will be aiming to drive home their first leg advantage and qualify for the UEFA Champions League semi-final, when they take on Porto this week.
Manchester City will be looking to overturn a narrow deficit when they host Tottenham for the second leg of the UEFA Champions League quarter-final on Wednesday.