A late Jamie Vardy goal cancelled out Pierre-Emerick Aubameyang's first-half strike as Leicester City held a ten-man Arsenal side to a 1-1 draw on Tuesday.
Christian Pulisic and Willian stood out while Andreas Christensen was underwhelming as Chelsea beat Crystal Palace 3-2 on Tuesday.
Manchester City will hope to bounce back after their shock defeat against Southampton when they take on Newcastle United at the Etihad on Wednesday.
Barcelona get ready for their first derby under Quique Setien as they host RCD Espanyol at Camp Nou on Matchday 35 of La Liga.
Wolves take on Sheffield United at Bramall Lane on Wednesday as both teams look to sustain their hopes of securing European football next season.
Chelsea's next fixtures will see them take on Crystal Palace in a tricky away game at Selhurst Park. Can the Blues strengthen their hold on fourth place?
Arsenal will be looking to build on their current winning momentum when they host Leicester City at the Emirates Stadium in the Premier League this midweek.
AC Milan are hoping to continue their excellent run of form since the restart when they lock horns with champions Juventus on Tuesday.
Antoine Griezmann and Lionel Messi ran the show as Barcelona put four past Villarreal at Estadio de la Ceramica on Sunday night.
Naby Keita and Sadio Mane were the difference makers while Alex Oxlade-Chamberlain squandered his opportunity as Liverpool beat Aston Villa 2-0 on Sunday.