Arsene Wenger has made eight changes to the side that was held to a draw by Atletico Madrid as Arsenal prepare to face Manchester United at Old Trafford.

January signing Konstantinos Mavropanos makes his Premier League debut for Arsenal, starting at the heart of the Arsenal defence alongside Calum Chambers. The only players retaining their places from the midweek game are David Ospina, Hector Bellerin and Granit Xhaka.

Meanwhile, Henrikh Mkhitaryan returns to the starting lineup against his former side after a short period on the sidelines due to injury, and will be looking to make a point. The Armenian will be combining with Pierre-Emerick Aubameyang in the Arsenal attack.

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