Sergio Romero has been entrusted with safeguarding United’s goal at the Balaidos. Wayne Rooney has no place in Mourinho’s starting XI and as a result, a returning Antonio Valencia has been entrusted with leading Manchester United as their captain on the night.

Henrikh Mkhitaryan returns to the squad ahead of Anthony Martial, with Jesse Lingard and MArcus Rashford retaining their place in the starting XI after their last match against Swansea. Marouane Fellaini will partner Ander Herrera and Paul Pogba in United’s midfield.

Matteo Darmian comes into the squad in place of Luke Shaw and he, alongside Eric Bailly and Daley Blind make up the rest of United’s defence in what seems to be a typical 4-2-3-1 formation by Jose Mourinho.

As for the hosts, Eduardo Berizzo has made a number of changes to the squad with former Liverpool hitman Iago Aspas and former Manchester City player John Guidetti both returning to the starting XI after being rested in their last match against Athletic Bilbao.

Striker Pione Sisto, defenders Gustavo Cabral, Jonny Castro, Hugo Mallo and midfielder Nemanja Radoja have all been reinstated into the starting XI for tonight’s tie against the Red Devils in what will likely be a typical 4-2-3-1 formation.

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