Liverpool finished the job on the final day of the season as goals from Wijnaldum, Coutinho and Lallana helped seal the Reds' passage through to the Champions League.
Jurgen Klopp could offer Daniel Sturridge a second consecutive league start for the first time this season as Roberto Firmino remains an injury doubt for Boro.
Juventus managed a 2-1 win over AS Monaco in the second leg in Turin to advance to the finals of the UEFA Champions League.
Raphael Varane and Jose Gimenez start for Real Madrid and Atletico Madrid respectively as the two sides meet in the second leg of the UEFA Champions League semifinal.
Juventus played a brilliant game of football to out-class their French opponents Monaco 2-1 to reach the final of the Champions League
Real Madrid defender Nacho could start at right-back in place of the injured Dani Carvajal.
Atletico Madrid will have a mountain to climb as they hope to recover a three-goal deficit over Real Madrid on Wednesday.
Sami Khedira is available for selection while Benjamin Mendy is doubtful as Juventus host AS Monaco on Tuesday.
Juventus will look to secure their place in the UEFA Champions League final when they host AS Monaco in the semifinal second leg on Tuesday.
Massimiliano Allegri masterminded a comfortable victory for the Serie A Champions over Leonardo Jardim's exciting young AS Monaco side at the Stade Louis II.