Arsenal will look to bounce back from their London derby defeat against West Ham United when they face Chelsea in what is another derby on Saturday.
Manchester United will be aiming to continue their winning run when they welcome Brighton & Hove Albion to Old Trafford on Saturday.
Liverpool will be looking to consolidate their position at the top of the Premier League table, when they take on Crystal Palace this weekend.
After their midweek defeat in the cup competition, Real Madrid will be itching to bounce back with a win when they face off against Sevilla in La Liga.
Barcelona completed the turnaround in their Round of 16 tie against Levante in stunning fashion, coasting to a 3-0 win at Camp Nou on Thursday.
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Barcelona will be hoping to overturn a first leg deficit and book a place in the Copa del Rey quarter-finals when they welcome Levante to Camp Nou on Thursday.
Real Madrid will be hoping to complete their progression to the Copa del Rey quarter-finals when they take on CD Leganes at the Butarque on Wednesday.
Manchester City will be aiming to close the gap to Liverpool back to four points when they host Wolves at the Etihad on Monday.
India will hope to create history and reach the knockout stages of the 2019 AFC Asian Cup when they face Bahrain in Sharjah in their final group tie on Monday.