Brentford and Everton will be desperate to return to winning ways when they face off at the Brentford Community Stadium on Sunday.
Paris Saint-Germain will be aiming to bounce back to winning ways when they take on Saint-Etienne at Stade Geoffroy-Guichard on Sunday.
Jordan Henderson, Virgil van Dijk and Diogo Jota have all been recalled to the starting lineup as Liverpool prepare to take on Southampton at Anfield.
Atletico Madrid will be aiming to maintain pressure on league leaders Real Madrid when they take on Cadiz on Sunday.
Tottenham Hotspur will be hoping to break into the European places when they lock horns with Burnley at Turf Moor on Sunday.
Nuno Tavares keeps his place while Mikel Arteta has chosen Martin Odegaard over Alexandre Lacazette for the game against Newcastle United.
Ousmane Dembele is in contention to start while Sergino Dest and Abde Ezzalzouli should feature from kickoff when Barcelona take on Villarreal in La Liga.
Trent Alexander-Arnold, Andrew Robertson and Diogo Jota are set to return when Liverpool welcome Southampton to Anfield on Saturday.
Mikel Arteta could make changes to the Arsenal lineup against Newcastle, with Kieran Tierney, Martin Odegaard, and Ainsley Maitland-Niles expected to start.
Defending champions Inter Milan will be looking to keep their good run of form going against Venezia and stay within touching distance of the top of the table.