Antoine Griezmann and Lionel Messi ran the show as Barcelona put four past Villarreal at Estadio de la Ceramica on Sunday night.
Naby Keita and Sadio Mane were the difference makers while Alex Oxlade-Chamberlain squandered his opportunity as Liverpool beat Aston Villa 2-0 on Sunday.
Tottenham Hotspur will be aiming to get back to winning ways when they play hosts to Everton in the Premier League on Monday night.
Real Madrid took another step towards being crowned the La Liga champions, when they defeated Athletic Bilbao 1-0 at San Mames on Sunday.
Divock Origi and Alex Oxlade-Chamberlain return while Jordan Henderson is rested as Liverpool prepare to take on Aston Villa at Anfield.
Naby Keita is expected to make only his second start since the resumption of the Premier League but who else could return when Liverpool take on Aston Villa?
Lionel Messi will get his well-deserved rest while Antoine Griezmann will return to the starting lineup when Barcelona take on Villarreal.
Real Madrid will be without the services of key men Eden Hazard and Raphael Varane when they take on Athletic Bilbao at San Mames on Sunday afternoon.
Bukayo Saka and Alexandre Lacazette were on target for Arsenal as they defeated Wolves 2-0 at the Molineux this weekend.
Inter Milan's latest Serie A fixture will witness them take on Bologna at San Siro. Will the Nerazzurri continue their winning run or does a surprise beckon?