Barcelona get ready for their first derby under Quique Setien as they host RCD Espanyol at Camp Nou on Matchday 35 of La Liga.
Wolves take on Sheffield United at Bramall Lane on Wednesday as both teams look to sustain their hopes of securing European football next season.
Alexandre Lacazette gets recalled to the starting lineup in place of Eddie Nketiah, while Hector Bellerin also starts against Leicester City.
Billy Gilmour makes only his second Premier League start as Chelsea get set to lock horns with Crystal Palace at Selhurst Park.
Aston Villa and Bournemouth are likely to go down along with Norwich as Premier League enters the last phase of the 2019-20 season.
Jorginho is expected to come in for the injured N'Golo Kante but what other changes will Frank Lampard make to his starting lineup against Crystal Palace?
Alexandre Lacazette is in line to start ahead of Eddie Nketiah for Arsenal when they take on Leicester City at the Emirates on Tuesday.
Chelsea's next fixtures will see them take on Crystal Palace in a tricky away game at Selhurst Park. Can the Blues strengthen their hold on fourth place?
Arsenal will be looking to build on their current winning momentum when they host Leicester City at the Emirates Stadium in the Premier League this midweek.
AC Milan are hoping to continue their excellent run of form since the restart when they lock horns with champions Juventus on Tuesday.