Everton and Arsenal played out a drab goalless draw at Goodison Park on Saturday, as new managers Carlo Ancelotti and Mikel Arteta watched from the stands.
A Kevin De Bruyne masterclass condemned Arsenal to an embarrassing 3-0 defeat at the hands of Manchester City at home on Sunday evening.
A late goal from Dan Gosling condemned Chelsea to a 1-0 defeat against Bournemouth at Stamford Bridge in Matchweek 17 of the 2019-20 Premier League.
A Mohamed Salah brace was enough to earn Liverpool all three points as they beat Watford 2-0 at Anfield in Saturday's lunch-time kick-off.
Pierre-Emerick Aubameyang scored a brace to rescue a point for Arsenal, who also had Bernd Leno to thank after holding Norwich City to a 2-2 draw.
Liverpool stretched their lead atop the Premier League table to 11 points, beating Brighton 2-1 at Anfield even as Alisson was sent off late in the game.
Sergio Ramos nearly went from hero to zero before Dani Carvajal struck an open goal to ensure a 2-1 win for Real Madrid over Alaves at the Mendizorrotza.
Barcelona had to work hard for all three points, as they came from behind to beat Leganes 2-1 at Estadio Municipal de Butarque on Saturday.
A goal apiece from Tammy Abraham and Christian Pulisic powered Chelsea through to a 2-0 win over Crystal Palace to triumph in the London derby.
Arsenal squandered a narrow one-goal lead with 15 minutes left to play as Wolves held them to a 1-1 draw at the Emirates on Saturday.