Manchester City will lock horns with a struggling Southampton side in the Carabao Cup Round of 16 stages at the Etihad Stadium on Tuesday night.
Manchester United will be aiming to end their four-game winless streak in the Premier League, when they take on Norwich City on Sunday evening.
Arsenal will welcome Crystal Palace at the Emirates on Sunday with an aim of turning things around for the rest of the season.
AC Milan will be hoping to put an end to their mixed run of form as they travel to Stadio Olimpico on Sunday to face AS Roma
Bayern Munich will look to get back to winnings ways in the Bundesliga when they host newly-promoted side Union Berlin at the Allianz Arena.
Atletico Madrid will be hoping to close down the gap to the top of the La Liga table when they lock horns against Athletic Bilbao at the Wanda Metropolitano.
The mother of all derbies in Germany is set to take place this Saturday as Borussia Dortmund travel to Gelsenkirchen to face FC Schalke in the Revierderby
Juventus will be looking to continue their unbeaten start to the new season when they take on newly promoted Lecce in matchweek 9 of the 2019-20 Serie A.
Manchester United will be aiming to go to the top of Group L of the 2019-20 UEFA Europa League when they take on leaders Partizan Belgrade on Thursday.
Borussia Monchengladbach will look to seal their first win in the UEFA Europa League this season when they lock horns with AS Roma tomorrow afternoon