Liverpool host West Ham United this weekend as they look to make it 4 wins in 4 and extend their unbeaten run at the fortress that is Anfield.
Barcelona will look to build on their victory over Juventus when they take on Deportivo Alaves at the Estadio Mendizorroza on Saturday.
Borussia Dortmund will hope to keep their winning run alive as they take on Arminia Bielefeld at the Schüco-Arena in gameweek six of the Bundesliga.
RB Leipzig are hoping to recover from their 5-0 defeat to Manchester United when they face Borussia Monchengladbach at the Borussia Park on Saturday.
Manchester City will be aiming to get back to winning ways in the Premier League when they face off against a struggling Sheffield United outfit this weekend.
Bayern Munich are aiming to continue their fantastic run of form when they travel to RheinEnergieStadion to face 1.FC Koln on Saturday.
AC Milan are looking to bounce back from their draw with AS Roma when they host Sparta Praha on Thursday, in the UEFA Europa League.
Tottenham Hotspur will hope to continue their winning run alive when they take on Royal Antwerp in their second UEFA Europa League game on Thursday.
Borussia Dortmund are in desperate need of a win when they play hosts to Zenit St. Petersburg in the UEFA Champions League on Wednesday.
Manchester City travel to Marseille to make it two wins out of two in the Champions League while the hosts look to cause an upset and register their first points of the season.