Real Madrid will look to end their 2021/22 La Liga campaign on a high when they take on Real Betis in their final match at the Santiago Bernabeu.
Everton have the chance to secure safety if they manage to secure a win over Crystal Palace at Goodison Park
Burnley's bid for survival continues on Thursday as they travel to the West Midlands to face Aston Villa for the second time in less than a fortnight.
Chelsea will look to seal the third-place finish in the Premier League table when they lock horns with Leicester City on home turf this midweek.
Liverpool will travel to St. Mary's Stadium this midweek to take on Southampton, hoping to keep the Premier League title race alive.
Arsenal aim to move into the driving seat in the race for the fourth spot in the Premier League when they visit Newcastle United on Monday night.
Juventus will look to end their disappointing campaign on a high when they take on SS Lazio in their final home game of the season.
Inter Milan will travel to Cagliari knowing very well that anything short of three points could mean kissing their chances of retaining the Scudetto goodbye.
Manchester City will be aiming to increase their lead at the top of the Premier League table when they face West Ham United this weekend.
AC Milan could move to within a game of securing the Serie A title should they defeat Atalanta at the San Siro on Sunday.
