Atletico Madrid will be hoping to close down the gap to the top of the La Liga table when they lock horns against Athletic Bilbao at the Wanda Metropolitano.
Barcelona edged Slavia Praha by the skin of their teeth on Wednesday, grabbing a 2-1 win to take command of the UEFA Champions League Group F.
Gerard Pique and Nelson Semedo are set to return when Barcelona take on Slavia Praha in their third UEFA Champions League fixture of the season.
A first half Toni Kroos goal was enough to hand Real Madrid all three points as they beat Galatasaray 1-0 to grab their first Champions League win of the season.
Barcelona will be aiming to pick up their second Champions League win of the season when they take on Slavia Praha at the Sinobo Stadium on Wednesday.
Toni Kroos and Eden Hazard are expected to return to the Real Madrid starting lineup when they face Galatasaray at the Turk Telekom Stadium.
Real Madrid will be looking for their first UEFA Champions League win of the season when they face Galatasaray at the Turk Telekom Stadium on Tuesday.
PSG are reportedly targeting a hijack of Real Madrid's summer pursuit of Tottenham superstar Christian Eriksen, who is set to exit the Premier League club.
Toni Kroos and Gareth Bale will miss out for Real Madrid through injury when they take on RCD Mallorca at the Iberostar Stadium on Saturday.
Antoine Griezmann is expected to return to the starting lineup as Barcelona gear up to take on SD Eibar at the Ipurua Municipal Stadium on Saturday.