Lionel Messi will not be eligible to play for Argentina for the coming three months after CONMEBOL handed the Barcelona icon a three-month ban from international football.
Brazil and Peru will have the chance to become the South American champions when they face off in the Copa America final at the Maracana.
Chile and Peru will battle it out at the Arena do Gremio on Wednesday night for a place in the finals of the 2019 Copa America.
A place in the 2019 Copa America will be on the line when South American powerhouses Brazil and Argentina face off at Estadio Mineirao
A place in the Copa America semi-finals will be on the line when Uruguay take on Peru at Itaipava Arena Fonte Nova on Saturday.
The second quarterfinal of the 2019 Copa America will see Venezuela go head to head against Lionel Messi's Argentina at the Maracana Stadium on Friday night.
Two of the tournament favourites will clash in Rio de Janeiro on Monday night, as Chile take on Uruguay in their final 2019 Copa America Group C encounter.
Top spot in Group A of the 2019 Copa America will be on the line when Brazil and Peru meet at Arena Corinthians on Saturday.
Chile will be looking to make it two wins in two matches in the 2019 Copa America, when they face off against Ecuador at the Fonte Nova Arena on Friday night.
Uruguay will be hoping to book their place in the quarter-finals of the 2019 Copa America when they take on Japan at Arena do Gremio.