Real Madrid ended their disappointing league campaign on a familiar note as they squandered a two-goal lead to be held to a 2-2 draw by Villarreal.
Chelsea won their 8th FA Cup on Saturday as they narrowly beat Manchester United 1-0 at Wembley courtesy an Eden Hazard penalty.
Real Madrid will look to end their league campaign on a winning note when they visit Estadio de la Ceramica to take on Villarreal on Saturday.
Chelsea need a win to keep their top four hopes alive as they travel to St. James' Park to face Newcastle United in the last gameweek of the Premier League.
Tottenham Hotspur will be aiming to end the season third on the table when they play hosts to Leicester City at Wembley on Sunday.
Liverpool will look to clinch a place in the top four when they host Brighton & Hove Albion at Anfield on Sunday in the final gameweek of the season.
Real Madrid will still be looking to leapfrog rivals Atletico Madrid into second place in La Liga as they host Celta Vigo on Saturday.
Manchester United clinched second spot on the Premier League table as they were held to a drab 0-0 draw by West Ham United at the London Stadium on Thursday.
Chelsea will be looking to continue piling on the pressure on their top four rivals as Huddersfield visit Stamford Bridge on Wednesday.
Manchester City will be aiming to return to winning ways when they play hosts to Brighton & Hove Albion at the Etihad on Wednesday.