Marcus Rashford and Luke Shaw are expected to start while Dean Henderson should replace David de Gea when Manchester United face Tottenham Hotspur.
Real Madrid are considering the possibility of re-signing Achraf Hakimi just a year after selling him to Inter Milan. Will the Moroccan be back in La Liga?
Karim Benzema and Federico Valverde impressed while Lionel Messi had a quiet night as Real Madrid beat Barcelona 2-1 in the El Clasico on Saturday.
Franck Kessie was the standout performer while Zlatan Ibrahimovic got sent off as AC Milan defeated Parma 3-1 on Saturday evening.
Jamal Musiala was one of the few positives as Bayern Munich were held to a 1-1 draw at home by Union Berlin on Saturday afternoon.
Atletico Madrid will be aiming to reclaim the top spot in the La Liga table when they take on Real Betis away from home in Matchweek 30 this weekend.
Arsenal will be hoping to return to winning ways when they face off against bottom-feeders Sheffield United in the Premier League this Sunday night.
Juventus will be hoping to make it two wins in two when they face off against Genoa at the Allianz Stadium this weekend in the 2020/21 Serie A.
Manchester United will be hoping to exact revenge on Tottenham Hotspur when the two teams face off this weekend in the 2020/21 Premier League.
Arsenal have reportedly been joined by neighbours and arch-rivals Tottenham Hotspur in the race to sign Crystal Palace attacker Wilfried Zaha.